| Institute |
Grant Holder |
Description |
| Brunel University |
Dr Amanda Harvey |
Regulating breast tumour cell survival through Bcl-x proteins: implications for therapeutic responses. |
| Brunel University |
Professor Robert Newbold |
Molecular & functional characterization of the chromosome-3-linked sequence, APRG1, as a novel breast cancer suppressor gene |
| Clare Hall Laboratories (Cancer Research UK), South Mimms |
Dr Simon Boulton |
Genome-wide RNAi to identify genes that confer synthetic lethality with BRCA1 |
| Guy's Hospital, London |
Dr Joy Burchell |
Interactions of tumour-associated immunogenic glycoforms of MUC1 with lectins of the immune system |
| Guy's Hospital, London |
Dr Joanna Morris |
Role of de-ubiquitinating enzymes and ubiquitin binding proteins in breast tumourigenesis |
| Guy's Hospital, London |
Dr John Maher |
Dual targeting of MUC1 and ErbB2 in the adoptive immunotherapy of breast cancer |
| Imperial College |
Professor Stephan Grimm |
Specific protein stabilisation for apoptosis induction in breast cancer |
| Imperial College |
Dr Simak Ali |
Mechanisms by which the estrogen receptor represses gene expression |
| Institute of Nuclear Medicine, University College London |
Dr Ashley Groves |
Tumour angiogenesis in breast cancer: correlation between FDG/PET, MRI, CT and histology |
| King's College, London |
Dr Joanna Morris |
BRCA1 gene variants in breast cancer |
| Leeds Institute for Molecular Medicine |
Dr Valerie Spiers |
Creation of a tissue microarray for the analysis of prognostic factors in male breast cancer |
| Leeds Institute for Molecular Medicine |
Dr Thomas Hughes |
Regulation of estrogen receptor beta by 5' untranslated regions in breast carcinogenesis |
| London School of Hygiene and Tropical Medicine |
Valerie McCormack |
Mammographic breast density in British young women: natural history and breast cancer prediction |
| London School of Hygiene and Tropical Medicine |
Dr Olivia Fletcher |
Polymorphisms, endogenous hormone levels and familial breast cancer risk in premenopausal women |
| Queen's University, Belfast |
Dr Jennifer Quinn |
Identification and characterisation of BRCA1 associated DNA damage dependent transcriptional targets |
| Queen's University, Belfast |
Dr Tracy Robson |
FKBPL-associated ER/Hsp90 chaperone complexes in breast cancer growth and survival |
| Royal Free and University College of London Medical School |
Professor Diana Kuh |
Effects of early life nutrition on the risk of breast cancer |
| Royal Marsden Hospital, London |
Professor John Yarnold |
Radiotherapy fraction size sensitivity is modulated by DNA repair & cell cycle checkpoints |
| The Open University, Milton Keynes |
Dr Sotiris Missailidis |
Aptamer technologies for diagnostic imaging and targeted therapy of breast cancer |
| University of Aberdeen |
Dr Tim Smith |
Targeted 18F-affibody conjugates for detection of herceptin responsive breast tumours by positron emission tomography |
| University of Aberdeen |
Dr Andrew Schofield |
Identification of genes involved in docetaxal resistance in breast cancer from chromosomes 7 and 10 |
| University of Birmingham |
Dr Farida Latif |
Functional characterization and role of the SLIT-ROBO gene family in breast cancer development |
| University of Birmingham |
Dr Moray Campbell |
NCoR1 interactions in breast cancer |
| University of Birmingham |
Dr Farida Latif |
Functional characterization of RASSF2 and AD037/RASSF4 proteins in relation to breast cancer development |
| University of Bristol |
Dr Ian Paterson |
The development of small molecule TGF-b antagonists to inhibit metastatic breast cancer |
| University of Cambridge |
Dr Christine Watson |
The role of caspases in mammary gland development and breast tumourigenesis |
| University of Cambridge |
Dr Ruth Warren |
POSH study - correlation of radiological features of breast cancer in women under 40 years with genetic, pathological and outcomes information |
| University of Cambridge |
Professor Ashok Venkitaraman |
Molecular pathogenesis of inherited breast cancer: A genome-wide screen for secondary genetic alterations required for the transformation of BRCA2-deficient cells |
| University of Cambridge |
Dr Christine Watson |
Estrogen receptor and the mammary epithelial cell hierarchy. |
| University of Cambridge |
Dr Paul Edwards |
Finding new genes in breast cancer by mapping chromosome translocations |
| University of Cardiff |
Dr Richard Clarkson |
Establishing a model of TRAIL sensitivity in breast cancer |
| University of Dundee |
Dr Mark Saville |
Identification of components of the ubiquitin system as targets for therapeutic intervention |
| University of Dundee |
Dr Jean-Christophe Bourdon |
Characterisation of p53 isoforms expression in breast cancer |
| University of Dundee |
Dr Frances Fuller-Pace |
Estrogen receptor alpha co-activation by p68 and its role in breast cancer. |
| University of East Anglia |
Professor Dylan Edwards |
The function of ADAMTS-8 and -15 in breast cancer |
| University of Glasgow |
Dr Torsten Stein |
The Role of TSC-22 in Mammary Gland Involution and Breast Cancer |
| University of Leicester |
Prof Rosemary Walker |
Altered myoepithelial cell function in cancer - containing breasts - a new risk marker? |
| University of London |
Professor Ian Mackenzie |
Breast cancer cells as models for developing therapeutic assays |
| University of Manchester |
Professor Charles Streuli |
Integrins and breast cancer progression |
| University of Manchester |
Dr Rachel Cowen |
Opticin: A potent anti-angiogenic/anti-proliferative agent for breast cancer therapy |
| University of Manchester |
Dr Robert Clarke |
Survival and self-renewal signalling pathways in human breast cancer stem cells |
| University of Manchester |
Dr Keith Brennan |
Role of Notch in proliferation and apoptosis of ductal carcinoma in situ |
| University of Manchester |
Dr Andrew Gilmore |
The regulation of anoikis by the Bcl-2 protein, Bid. |
| University of Manchester |
Dr Robert Clarke |
Identification of signalling pathways that regulate human breast stem cells |
| University of Newcastle |
Professor Bruce Westley |
The potential value of targeting the IGF signalling pathway in breast cancer |
| University of Nottingham |
Dr Stewart Martin |
The thioredoxin and related redox systems as targets in breast cancer |
| University of Nottingham |
Dr Andrew Green |
Transcriptional/translational analysis of breast cancer providing - a modern clinical classification system |
| University of Oxford |
Dr Madalena Tarsounas |
Roles of BRCA1 and BRCA2 Tumour Suppressors in Telomere Maintenance |
| University of Sheffield |
Dr Ingunn Holen |
Effects of combined drug treatments on breast tumours in vivo |
| University of Sheffield |
Professor Claire Lewis |
Regulation of the pro-angiogenic functions of Tie-2+ monocytes by angiopietin-2 and hypoxia |
| University of Sheffield |
Dr Angela Cox |
The role of CASP8D302H and other apoptosis gene variants in breast cancer |
| University of Southampton |
Dr Diana Eccles |
Can tumour phenotyping identify hereditary breast cancer predisposition? |
| University of Southampton |
Dr Jeremy Blaydes |
CtBP proteins: role and regulation in breast cancer response to chemotherapy |
| University of Southampton |
Dr Graham Sale |
Role of protein kinase B in breast cancer |
| University of Wales, Cardiff |
Professor Bharat Jasani |
The value of p53 as a predictive marker of response to chemotherapy in breast cancer |
| University of West of England |
Dr Diana Harcourt |
The psychosocial impact of ductal carcinoma in situ (DCIS) |
