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Completed research projects in 'All regions'

Institute Grant Holder Description
Addenbrookes Hospital and Ipswich Hospital NHS Trust Dr Charlotte Coles Development of complex radiotherapy techniques in breast cancer
Barts and the London Hospital Professor Louise Jones The role of 6 integrin expression on myoepithelial cell function in DCIS
Bradford University Dr Jason Gill Involvement of the PPARs in the development and treatment of breast cancer
Brunel University Professor Janet Arrand The role of DNA repair genes in radiosensitivity and breast cancer predisposition
Christie Hospital Dr Michelle Harvie The effect of intermittent vs. chronic energy restriction on breast cancer risk biomarkers
Clare Hall Laboratories (Cancer Research UK), South Mimms Dr Stephen West Identification of novel recombination/repair factors and their role in tumour avoidance
Clare Hall Laboratories (Cancer Research UK), South Mimms Dr Simon Boulton Genetic and biochemical characterization of BRAC1/BARD1 orthologues in C.elegans
Clare Hall Laboratories (Cancer Research UK), South Mimms Dr Stephen West Cellular and biochemical functions of BRCA2
Department of Pathology, Royal Victoria Infirmary Professor Bruce Westley Mechanism of oestrogen regulated proliferation of breast cancer cells
Guy's Hospital, London Professor Joyce Taylor-Papadimitriou Epigenetic regulation of expression of BRCA1 and checkpoint genes by PLU- 1/JARID1B
Guy's Hospital, London Professor Joyce Taylor-Papadimitriou Sialyl Tn and the immune response in breast cancer patients
Imperial College Professor Mustafa Djamgoz A novel mechanism in the action of oestrogen in breast cancer: Regulation of functional voltage-gated Na+ channel (nNav1.5) expression
Imperial College Dr David Mann The Linda Jacobs Breast Cancer Campaign PhD studentship Cyclin D1 and the DNA damage response
Imperial College Dr Ximena Montano The role of SHP-1 in the activation of the nerve growth factor receptor, trkA, by p53 in breast cancer
Institue of Child Health, University College London Dr Vishwanie Budhram-Mahadeo Brn-3b transcription factor in breast tumourigenesis-mechanism of regulating cellular growth
Institute of Cancer Research, London Dr Ros Eeles Expression profiling of normal cells from BRCA1/2 mutation carriers after DNA damage
Institute of Cancer Research, London Professor Nazneen Rahman Identification of breast cancer susceptibility genes by mutational screening of candidate genes from DNA Repair pathways
John Radcliffe Hospital, Oxford Dr Alison Banham Investigations of FOXP1 as a novel oestrogen receptor co-regulator in breast cancer
Keele University Professor Gwyn Williams Production of breast cancer lines for functional expression cloning of apoptosis genes
King's College, London Dr John Maher Use of MUC1-specific M-CSF-responsive T-Cells for breast cancer
King's College, London Professor Livio Mallucci A new approach to breast cancer control: use of beta-GBP, a novel cytokine
King's College, London/Guy's Hospital Professor Tony Ng Chemokines and breast cancer
London Research Institute Dr Erik Sahai Role of Fos and Jun family proteins in tumour cell motility in vivo
Ninewells Hospital and Medical School, Dundee Dr Thomas Friedberg Cancer risk and therapy outcome: A mechanistic link to CYP1B1 polymorphism.
Northwick Park - St Mark's NHS Trust Professor Stella Knight Potentiation of immunity of breast carcinomas for tumour therapy
Paterson Institute for Cancer Research, University of Manchester Dr Robert Clarke Investigation of the properties of isolated human stem cells
Paterson Institute for Cancer Research, University of Manchester Dr Robert Clarke The role of cyclin-dependent kinase inhibitors in human breast cell differentiation
Princess Anne Hospital, Southampton Dr Diana Eccles The development of Melt-MADGE mutation scanning for the BRCA1 gene
Queen's University, Belfast Dr David Waugh Cathepsin K and MMP-9 in CD44-promoted breast cancer metastasis
Queen's University, Belfast Dr Paul D Harkin Define the mechanistic basis of BRCA1 induced mitotic arrest in response to paclitaxel
Royal College of Surgeons of England Mr Jonathon Fountain Breast Cancer Campaign Tutor
Royal College of Surgeons of England Mr Dick Rainsbury The Breast Cancer Campaign Tutor at the Royal College of Surgeons
Royal College of Surgeons of England Mr Dick Rainsbury Course on the management of breast disease
Royal College of Surgeons of England Mr Dick Rainsbury BASO Breast Speciality Group Symptomatic Guildelines 1998
Royal Free and University College of London Medical School Dr Kerry Chester Production and Characterisation of a Recombinant anti-HER2 diabody for Breast Cancer Imaging
Royal Holloway, University of London Dr Mark Crompton The role of the Brk tyrosine kinase in breast cancer progression
Royal Marsden & Institute of Cancer Research, London Professor Mitch Dowsett Cell filtration-laser scanning cytometry for characterisation of circulating breast cancer cells
Royal Marsden & Institute of Cancer Research, London Dr Stephen Johnston The role of ER/AP-1 activation in endocrine resistant human breast cancer
Royal Marsden & Institute of Cancer Research, London Dr Ros Eeles Study in the Clinical Management of BRCA1 and BRCA2 gene carriers
South Manchester University Hospital Professor Nigel Bundred The role of notch in the development and progression of ductal carcinoma in situ (DCIS)
South Manchester University Hospital Dr Paul D Harkin Characterisation of BRCA1 mediated cell death in response to antimicrotubule agents
St George's Hospital Medical School, London Dr Kay Colston Molecular and functional relationship between vitamin D receptor polymorphisms and breast cancer risk
St Thomas' Hospital Dr Kairbaan Hodivala Dilke Investigating the role of a 3-integrin in angiogenesis
St Thomas' Hospital Professor Ian Hart E-cadherin regulation in breast cancer: role of methylation status
St Thomas' Hospital Professor Ian Hart Molecular cloning and expression of the human hyaluronan receptor (RHAMM) in breast cancer cells
St Thomas' Hospital Professor Ian Hart Cell adhesionin lobular carcinoma of the breast
St Thomas' Hospital Dr Richard Camplejohn Response to chemotherapy in breast cancer: the role of p53 and apoptosis
St Thomas's Hospital, London & Aston University, Birmingham Dr Beth Grunfeld Factors influencing delay behaviour in breast cancer
Univerity of Glasgow Dr Grant Gallagher The role of interleukin 10 in breast cancer
University College London Dr Magali Williamson The role of Plexin B1 mutations in breast cancer progression
University of Aberdeen Dr Andrew Schofield Characterisation of genetic events involved in resistance to chemotherapy in breast cancer
University of Birmingham Dr Fedor Berditchevski The role of the tumor specific antigen L6 in migration and invasion of breast cancer
University of Birmingham Dr Roger Grand A possible role for C teminal binding protein in the generation of breast tumors
University of Birmingham Institute for Cancer Studies Dr Fedor Berditchevski The role of the metastasis-suppressor tetraspanin CD82/KAI-1 in regulation of signalling in breast cancer cells.
University of Birmingham Institute for Cancer Studies Dr Fedor Berditchevski The role of the tetraspanin KA1-1/CD82 in signalling induced by ErbB receptors
University of Birmingham Medical School Dr Farida Latif Role of ROBO1 (DUTT1) a candidate tumour suppressor gene at 3p12 and its ligands the SLIT genes in breast cancer development
University of Birmingham Medical School Dr Farida Latif Characterisation and functional analysis of candidate breast tumour suppressor genes from the human chromosomal region 3p21.3
University of Birmingham Medical School Professor Lawrence Young CD40 as a novel therapeutic target for breast cancer
University of Birmingham Medical School Dr Farida Latif Isolation, characterisation and functional analysis of tumour suppressor genes involved in breast cancer located on the short arm of human chromosome three (3p)
University of Bristol Dr Claire Perks Does IGFBP-2 promote breast cancer cell growth by acting as a novel regulator of PTEN?
University of Bristol Professor George Davey-Smith Early life influences on breast density and breast cancer risk
University of Cambridge Dr Paul Edwards Mapping the breast cancer genome
University of Cambridge Professor Jim Metcalfe TGF /ALK1 signalling effects on breast tumour metastasis
University of Cambridge Professor Jim Metcalfe Transforming growth factor-B signalling in breast cancer.
University of Cambridge Dr Paul Edwards Chromosome translocations that target NRG1/heregulin in breast cancers
University of Cambridge Dr Grace Callagy Molecular pathology of sporadic breast cancer
University of Cardiff Professor Trevor Dale Investigating h-Prune activation of Wnt signalling in breast cancer
University of Cardiff Dr Kathryn Taylor The role of zinc transporter HKE4 in breast cancer
University of Cardiff Dr Julia Gee Investigation of GFR 1 in experimental and clinical breast cancer
University of Cardiff Professor Trevor Dale Wnt signalling and lobular development in the mammary gland
University of Cardiff Dr Julia Gee Identification of genes associated with endocrine resistance in breast cancer
University of Dundee Dr Ana M Schor Endogenous control of angiogenesis by endothelial cells. Identification of MSF inhibitor
University of Dundee Dr Ana M Schor Evaluation of MSF expression for breast cancer diagnosis and prognosis
University of Dundee Seth Schor Initial assessment of MSF expression in breast cancer: association with angiogenesis markers
University of East Anglia Professor Dylan Edwards The roles of ADAMTS metalloproteinases in breast cancer
University of East Anglia/Fakenham Medical Practice, Norwich Dr Carly Hughes Breast Cancer Follow-up: A focus group study
University of Edinburgh Dr Dana Faratian Using systems biology as a novel tool for predicting cellular responses to Herceptin and tamoxifen
University of Edinburgh Professor Bill Miller Socio-economic status and the natural history of breast cancer
University of Essex Dr Elena Klenova Effects of chemotherapy on BORIS expression in leukocytes of breast cancer patients
University of Essex Dr Elena Klenova Role of poly(ADP-ribosyl)ation of CTCF in breast tumourigenesis
University of Essex Dr Elena Klenova The role of a transcription factor, CTCF, in breast tumorigenesis
University of Glasgow Professor Iain Morgan Identification of TopBP1 target genes in normal and DNA damaged breast cancer cells
University of Kent Professor William Gullick Why do c-erbB-2/HER2 positive breast cancer patients fail to respond to Herceptin?
University of Leeds Dr Elizabeth Valleley Characterisation of the tumour suppressor gene ZAC in breast tissue
University of Leeds Dr Valerie Spiers Mechanisms of loss of oestrogen receptor in breast cancer
University of Leicester Professor Louise Jones Functional and clinical significance of altered tenascin expression in the breast
University of Leicester Dr Roger James Identification of MHC class II-restricted tumour antigens associated with breast cancer
University of Liverpool Dr Roger Barraclough The identification of functional domains in the metastasis-inducing, calcium-binding protein, p9Ka
University of Manchester Dr Michelle Webb Development of a functional assay for BRCA1 missense mutations
University of Manchester Dr Keith Brennan Role of Notch signalling in acquired apoptosis resistance in mammary epithelial cells
University of Manchester Professor Charles Streuli Inhibitor of apoptosis proteins in breast cancer
University of Manchester Dr Keith Brennan A role for Notch signalling in human breast cancer?
University of Manchester Dr Neil Anderson Primary culture of ductal carcinoma in situ to investigate the factors regulating epithelial cell proliferation and apoptosis
University of Manchester Dr Keith Brennan A role for Notch signalling in human breast cancer
University of Manchester Dr Michelle Webb Elucidating the domain structure and characterising the molecular interactions of BRCA2
University of Manchester Dr Neil Anderson The role of protein kinase B in breast cancer
University of Manchester Dr Stephen Taylor Why are some breast cancers resistant to taxol?
University of Manchester Dr Anthony Threlfall Survey Report on Breast Cancer Awareness Month, 1999
University of Newcastle Dr Barbara Durkacz Fighting breast cancer by inhibition of NF-kB
University of Newcastle Dr Michael Tilby Specific senstitization of breast cancer to treatment using novel DNA repair inhibitors
University of Newcastle Dr Nicola Curtin Investigation of the therapeutic potential of novel CDK inhibitors in breast cancer
University of Newcastle Dr Barbara Durkacz Determination of mechanisms driving breast cancer-specific poly (ADP-Ribose) polymerase
University of Newcastle Professor Bruce Westley Expression of the insulin receptor substrate family of proteins in breast cancer
University of Oxford Dr Nicholas D Lakin Regulation of BRCA2 in response to DNA damage
University of Reading Dr Philippa Darbre Identification of novel genes in endocrine resistance of breast cancer
University of Reading Dr Philippa Darbre Identification of novel genes in endocrine resistance of breast cancer
University of Sheffield Dr Ingunn Holen Effects of combined drug treatment in breast cancer angiogenesis
University of Sheffield Professor Carl GW Smythe Molecular mechanism of Chk1 checkpoint deficiency in BRCA1-deficient breast cancer cells.
University of Sheffield Dr Ingunn Holen Advantages of combined treatment with zoledronic acid and cytotoxic drugs in breast cancer
University of Sheffield Dr Nicola Brown Role of macrophages in breast tumour angiogenesis
University of Sheffield Medical School Dr Angela Cox The genetic epidemiology of DNA recombination repair genes in breast cancer
University of Southampton Professor Graham Packham (left) with researcher, Adam Sharp Regulation of ?-catenin expression by acetylation in breast cancer cells
University of Southampton Dr Jeremy Blaydes Regulation of p53-dependent and -independent breast cancer cell apoptosis by CtBPs.
University of Southampton Professor Jessica Corner A study of the experience of living with metastatic breast cancer
University of Southampton Professor Graham Packham (left) with researcher, Adam Sharp Small molecule inhibitors of the BAG-1: HSC/HSP70 interaction
University of St Andrews, Fife Dr Peter E Bryant The role of topoisomerase II expression in breast cancer susceptibility
University of St Andrews, Fife Professor Richard Iggo Role of NRCAM in breast cancer
University of St Andrews, Fife Professor Michael Steel Characterisation of Scottish founder mutations in BRCA1 and BRCA 1
University of Wales College of Medicine, Cardiff Dr Jonathon Gray Attitudes of men with breast cancer in the United Kingdom
University of Wales, Cardiff Professor Wen Jiang Development of NK4, a HGF antagonist, in the treatment of breast cancer
University of Wales, Cardiff Professor Wen Jiang NK4, a new HGF/SF antagonist, as a novel anti-metastasis tool in breast cancer
Western General Hospital, Edinburgh Dr Theodore Hupp The Breast Cancer Campaign Garfield Weston Foundation PhD Studentship: The role of AG-2 as a novel inhibitor of the p53 response to DNA damage